In vivo anti-inflammatory and in vitro antioxidant potential of crude fractions from Pyrus bretschneideri Rehd

Abstract

The present study was conducted to evaluate the anti-inflammation and antioxidant properties of Pyrus bretschneideri Rehd. using various solvents, such as petroleum ether (PE), ethyl acetate (EtOAc) and n-butanol (n-BuOH). The antioxidant activities of crude extracts were evaluated by using the DPPH test, Β-Carotene bleaching method and FRAP assay. The EtOAc extract exhibited high anti-inflammation activities, followed by n-BuOH and ethanol extracts (EtOH). The n-BuOH fraction showed the best antioxidant activities and the EtOAc fraction showed the best anti-inflammatory activities.